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Protocol to Generate and Characterize Potent and Selective WNT Mimetic Molecules
WNT signaling is crucial for embryonic development, adult tissue homeostasis, and injury repair. The poor biophysical characteristics of WNTs and their lack of receptor selectivity have hindered their use as research tools or potential therapeutics. We have developed a platform to generate potent, s...
Autores principales: | Chen, Hui, Lu, Chenggang, Lee, Sung-Jin, Li, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580111/ https://www.ncbi.nlm.nih.gov/pubmed/33111090 http://dx.doi.org/10.1016/j.xpro.2020.100043 |
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