The off-label use of anakinra in pediatric systemic autoinflammatory diseases

Interleukin 1 (IL-1), a central mediator of innate immunity, is considered a master cytokine of local and systemic inflammation. IL-1 has emerged as pivotal in the pathogenesis of autoinflammatory diseases (AIDs), and blockade of its pathway has become a crucial target for therapy. Anakinra (ANA), a...

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Detalles Bibliográficos
Autores principales: Maniscalco, Valerio, Abu-Rumeileh, Sarah, Mastrolia, Maria Vincenza, Marrani, Edoardo, Maccora, Ilaria, Pagnini, Ilaria, Simonini, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580132/
https://www.ncbi.nlm.nih.gov/pubmed/33149772
http://dx.doi.org/10.1177/1759720X20959575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580132/
https://www.ncbi.nlm.nih.gov/pubmed/33149772
http://dx.doi.org/10.1177/1759720X20959575

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