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Functional reconstruction of severe hand injuries using allogeneic tendons: a retrospective study
OBJECTIVE: To evaluate the effectiveness and safety of allogeneic tendons for functional reconstruction of severe hand injuries. METHODS: From August 2007 to July 2014, we performed functional reconstruction with tendon allografts for severe hand injuries affecting two or more tendons. At the final...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580153/ https://www.ncbi.nlm.nih.gov/pubmed/33059512 http://dx.doi.org/10.1177/0300060520955032 |
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author | Wang, Gu Heng Mao, Tian Xing, Shu Guo Chen, Ya Lan Zhang, Yu Xuan Xie, Ren Guo Zhou, Xiao Zhong |
author_facet | Wang, Gu Heng Mao, Tian Xing, Shu Guo Chen, Ya Lan Zhang, Yu Xuan Xie, Ren Guo Zhou, Xiao Zhong |
author_sort | Wang, Gu Heng |
collection | PubMed |
description | OBJECTIVE: To evaluate the effectiveness and safety of allogeneic tendons for functional reconstruction of severe hand injuries. METHODS: From August 2007 to July 2014, we performed functional reconstruction with tendon allografts for severe hand injuries affecting two or more tendons. At the final follow-up, we assessed total active motion (TAM); pincer pinch strength; grip strength; Disabilities of the Arm, Shoulder, and Hand (DASH) score; degree of satisfaction; and adhesion. We measured the white blood cell count, C-reactive protein concentration, erythrocyte sedimentation rate, total T-cell count, and CD4(+)T/CD8(+)T ratio to evaluate the immune response and check for infection. RESULTS: Ten patients received 26 allogeneic tendons to reconstruct hand function. The average follow-up period was 50.0 months (range, 24–82 months). The TAM was 126.4° (12°–253°), pincer pinch strength was 0.83 kg (0–4.5 kg), and grip strength was 13.69 kg (4–41.5 kg). The DASH score was 14.25 (3.3–30.8), and seven and three patients were satisfied and partially satisfied, respectively. One patient developed tendon adhesion. All immune and infectious parameters were within the reference range. CONCLUSION: Functional reconstruction using allogeneic tendons for severe hand injuries with multiple tendon defects was effective and safe; however, more research is needed. |
format | Online Article Text |
id | pubmed-7580153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-75801532020-11-03 Functional reconstruction of severe hand injuries using allogeneic tendons: a retrospective study Wang, Gu Heng Mao, Tian Xing, Shu Guo Chen, Ya Lan Zhang, Yu Xuan Xie, Ren Guo Zhou, Xiao Zhong J Int Med Res Retrospective Clinical Research Report OBJECTIVE: To evaluate the effectiveness and safety of allogeneic tendons for functional reconstruction of severe hand injuries. METHODS: From August 2007 to July 2014, we performed functional reconstruction with tendon allografts for severe hand injuries affecting two or more tendons. At the final follow-up, we assessed total active motion (TAM); pincer pinch strength; grip strength; Disabilities of the Arm, Shoulder, and Hand (DASH) score; degree of satisfaction; and adhesion. We measured the white blood cell count, C-reactive protein concentration, erythrocyte sedimentation rate, total T-cell count, and CD4(+)T/CD8(+)T ratio to evaluate the immune response and check for infection. RESULTS: Ten patients received 26 allogeneic tendons to reconstruct hand function. The average follow-up period was 50.0 months (range, 24–82 months). The TAM was 126.4° (12°–253°), pincer pinch strength was 0.83 kg (0–4.5 kg), and grip strength was 13.69 kg (4–41.5 kg). The DASH score was 14.25 (3.3–30.8), and seven and three patients were satisfied and partially satisfied, respectively. One patient developed tendon adhesion. All immune and infectious parameters were within the reference range. CONCLUSION: Functional reconstruction using allogeneic tendons for severe hand injuries with multiple tendon defects was effective and safe; however, more research is needed. SAGE Publications 2020-10-15 /pmc/articles/PMC7580153/ /pubmed/33059512 http://dx.doi.org/10.1177/0300060520955032 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Retrospective Clinical Research Report Wang, Gu Heng Mao, Tian Xing, Shu Guo Chen, Ya Lan Zhang, Yu Xuan Xie, Ren Guo Zhou, Xiao Zhong Functional reconstruction of severe hand injuries using allogeneic tendons: a retrospective study |
title | Functional reconstruction of severe hand injuries using allogeneic tendons: a retrospective study |
title_full | Functional reconstruction of severe hand injuries using allogeneic tendons: a retrospective study |
title_fullStr | Functional reconstruction of severe hand injuries using allogeneic tendons: a retrospective study |
title_full_unstemmed | Functional reconstruction of severe hand injuries using allogeneic tendons: a retrospective study |
title_short | Functional reconstruction of severe hand injuries using allogeneic tendons: a retrospective study |
title_sort | functional reconstruction of severe hand injuries using allogeneic tendons: a retrospective study |
topic | Retrospective Clinical Research Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580153/ https://www.ncbi.nlm.nih.gov/pubmed/33059512 http://dx.doi.org/10.1177/0300060520955032 |
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