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Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease
Trichloroethylene exposure is a major risk factor for pulmonary veno-occlusive disease. We demonstrated that trichloroethylene alters the endothelial barrier integrity, at least in part, through vascular endothelial (VE)-Cadherin internalisation, and suggested that this mechanism may play a role in...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580174/ https://www.ncbi.nlm.nih.gov/pubmed/33149891 http://dx.doi.org/10.1177/2045894020907884 |
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| author | Caliez, Julien Riou, Marianne Manaud, Grégoire Nakhleh, Morad K. Quatredeniers, Marceau Rucker-Martin, Catherine Dorfmüller, Peter Lecerf, Florence Vinhas, Maria C. Khatib, Salam Haick, Hossam Cohen-Kaminsky, Sylvia Humbert, Marc Montani, David Perros, Frédéric |
| author_facet | Caliez, Julien Riou, Marianne Manaud, Grégoire Nakhleh, Morad K. Quatredeniers, Marceau Rucker-Martin, Catherine Dorfmüller, Peter Lecerf, Florence Vinhas, Maria C. Khatib, Salam Haick, Hossam Cohen-Kaminsky, Sylvia Humbert, Marc Montani, David Perros, Frédéric |
| author_sort | Caliez, Julien |
| collection | PubMed |
| description | Trichloroethylene exposure is a major risk factor for pulmonary veno-occlusive disease. We demonstrated that trichloroethylene alters the endothelial barrier integrity, at least in part, through vascular endothelial (VE)-Cadherin internalisation, and suggested that this mechanism may play a role in the development of pulmonary veno-occlusive disease. |
| format | Online Article Text |
| id | pubmed-7580174 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | SAGE Publications |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-75801742020-11-03 Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease Caliez, Julien Riou, Marianne Manaud, Grégoire Nakhleh, Morad K. Quatredeniers, Marceau Rucker-Martin, Catherine Dorfmüller, Peter Lecerf, Florence Vinhas, Maria C. Khatib, Salam Haick, Hossam Cohen-Kaminsky, Sylvia Humbert, Marc Montani, David Perros, Frédéric Pulm Circ Research Letter Trichloroethylene exposure is a major risk factor for pulmonary veno-occlusive disease. We demonstrated that trichloroethylene alters the endothelial barrier integrity, at least in part, through vascular endothelial (VE)-Cadherin internalisation, and suggested that this mechanism may play a role in the development of pulmonary veno-occlusive disease. SAGE Publications 2020-10-16 /pmc/articles/PMC7580174/ /pubmed/33149891 http://dx.doi.org/10.1177/2045894020907884 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
| spellingShingle | Research Letter Caliez, Julien Riou, Marianne Manaud, Grégoire Nakhleh, Morad K. Quatredeniers, Marceau Rucker-Martin, Catherine Dorfmüller, Peter Lecerf, Florence Vinhas, Maria C. Khatib, Salam Haick, Hossam Cohen-Kaminsky, Sylvia Humbert, Marc Montani, David Perros, Frédéric Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease |
| title | Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease |
| title_full | Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease |
| title_fullStr | Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease |
| title_full_unstemmed | Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease |
| title_short | Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease |
| title_sort | trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease |
| topic | Research Letter |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580174/ https://www.ncbi.nlm.nih.gov/pubmed/33149891 http://dx.doi.org/10.1177/2045894020907884 |
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