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A Phase I, Randomized, Single-Dose Study to Evaluate the Biosimilarity of QL1206 to Denosumab Among Chinese Healthy Subjects

OBJECTIVE: This study was conducted to explore the tolerance, variability, pharmacokinetics (PK), and pharmacodynamics (PD) of denosumab biosimilar (QL1206) in healthy Chinese subjects. METHODS: This is a randomized, double-blind, two-arm, parallel study performed to examine the bioequivalence of de...

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Detalles Bibliográficos
Autores principales:	Zhang, Hong, Wu, Min, Zhu, Xiaoxue, Li, Cuiyun, Li, Xiaojiao, Sun, Jixuan, Liu, Chengjiao, Liu, Quan, Wei, Wei, Niu, Junqi, Ding, Yanhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580200/ https://www.ncbi.nlm.nih.gov/pubmed/33132906 http://dx.doi.org/10.3389/fphar.2020.01329

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