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Protocol for Identification and Removal of Doublets with DoubletDecon

Retention of multiplet captures in single-cell RNA sequencing (scRNA-seq) data can hinder identification of discrete or transitional cell populations and associated marker genes. To overcome this challenge, we created DoubletDecon to identify and remove doublets, multiplets of two cells, by using a...

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Detalles Bibliográficos
Autores principales: DePasquale, Erica A.K., Schnell, Daniel, Chetal, Kashish, Salomonis, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580240/
https://www.ncbi.nlm.nih.gov/pubmed/33111118
http://dx.doi.org/10.1016/j.xpro.2020.100085