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High-Throughput Chemical Screening for Inhibitors of Salmonella Pathogenicity Island 2
Anti-virulence therapies are under active investigation as antibiotic alternatives; however, their identification from large-scale chemical libraries poses a unique challenge. The dispensability of virulence factors for growth in vitro precludes conventional, optical density-based screening methods....
Autores principales: | Tsai, Caressa N., Coombes, Brian K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580248/ https://www.ncbi.nlm.nih.gov/pubmed/33111100 http://dx.doi.org/10.1016/j.xpro.2020.100057 |
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