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High-Throughput Chemical Screening for Inhibitors of Salmonella Pathogenicity Island 2

Anti-virulence therapies are under active investigation as antibiotic alternatives; however, their identification from large-scale chemical libraries poses a unique challenge. The dispensability of virulence factors for growth in vitro precludes conventional, optical density-based screening methods....

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Detalles Bibliográficos
Autores principales: Tsai, Caressa N., Coombes, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580248/
https://www.ncbi.nlm.nih.gov/pubmed/33111100
http://dx.doi.org/10.1016/j.xpro.2020.100057

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