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Functional Genomics in Pancreatic β Cells: Recent Advances in Gene Deletion and Genome Editing Technologies for Diabetes Research
The inheritance of variants that lead to coding changes in, or the mis-expression of, genes critical to pancreatic beta cell function can lead to alterations in insulin secretion and increase the risk of both type 1 and type 2 diabetes. Recently developed clustered regularly interspaced short palind...
Autores principales: | Hu, Ming, Cherkaoui, Ines, Misra, Shivani, Rutter, Guy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580382/ https://www.ncbi.nlm.nih.gov/pubmed/33162936 http://dx.doi.org/10.3389/fendo.2020.576632 |
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