Cargando…

Study of Acid-Base Disorders and Biochemical Findings of Patients in a Tertiary Care Hospital: A Descriptive Cross-sectional Study

INTRODUCTION: Acid base disorder is a condition characterized by alteration in blood pH by the imbalance between the components of blood leading to a life threatening situation. The main aim of this study was to find the prevalence of acid-base disorders and biochemical findings of such disorders in...

Descripción completa

Detalles Bibliográficos
Autores principales: Shreewastav, Rupesh Kumar, Jaishi, Krishna Prasad, Pandey, Madan Raj, Singh, Ganesh Prasad, Singh, Arambam Giridhari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580413/
https://www.ncbi.nlm.nih.gov/pubmed/32335656
http://dx.doi.org/10.31729/jnma.4722
_version_ 1783598787939270656
author Shreewastav, Rupesh Kumar
Jaishi, Krishna Prasad
Pandey, Madan Raj
Singh, Ganesh Prasad
Singh, Arambam Giridhari
author_facet Shreewastav, Rupesh Kumar
Jaishi, Krishna Prasad
Pandey, Madan Raj
Singh, Ganesh Prasad
Singh, Arambam Giridhari
author_sort Shreewastav, Rupesh Kumar
collection PubMed
description INTRODUCTION: Acid base disorder is a condition characterized by alteration in blood pH by the imbalance between the components of blood leading to a life threatening situation. The main aim of this study was to find the prevalence of acid-base disorders and biochemical findings of such disorders in patients in a tertairy care hospital. METHODS: This descriptive cross-sectional study was conducted in Nobel Medical College Teaching Hospital from 1(st) September, 2018 to 31(st) August, 2019. Ethical apporoval was taken from Institutional Review Committee. All the patients presented to emergency department, intensive care units and wards were included during the study period. Data were entered and calculations were done in Microsoft Excel, point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. RESULTS: Out of arterial blood gas analysis of 1144 patients, the prevalence of acid base disorders was 718 (62.76%) at 95% Confidence Interval (59.96-65.56%). Simple and mixed acid base disorders were observed in 332 (46.24%) and 386 (53.76%) patients respectively. Respiratory alkalosis was most common among 134 (40.36%) cases in simple acid base disorder whereas metabolic acidosis and respiratory alkalosis was most common among 204 (52.85%) in mixed acid base disorder. All types of disorders were observed more in elderly people (41-60 and >60 age group) than other age groups. CONCLUSIONS: Acid base disorder was found to be more common in very ill patients in emergency and intensive care units. Mixed acid base disorder was the most common with male and elderly patients in predominance.
format Online
Article
Text
id pubmed-7580413
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Journal of the Nepal Medical Association
record_format MEDLINE/PubMed
spelling pubmed-75804132020-11-30 Study of Acid-Base Disorders and Biochemical Findings of Patients in a Tertiary Care Hospital: A Descriptive Cross-sectional Study Shreewastav, Rupesh Kumar Jaishi, Krishna Prasad Pandey, Madan Raj Singh, Ganesh Prasad Singh, Arambam Giridhari JNMA J Nepal Med Assoc Original Article INTRODUCTION: Acid base disorder is a condition characterized by alteration in blood pH by the imbalance between the components of blood leading to a life threatening situation. The main aim of this study was to find the prevalence of acid-base disorders and biochemical findings of such disorders in patients in a tertairy care hospital. METHODS: This descriptive cross-sectional study was conducted in Nobel Medical College Teaching Hospital from 1(st) September, 2018 to 31(st) August, 2019. Ethical apporoval was taken from Institutional Review Committee. All the patients presented to emergency department, intensive care units and wards were included during the study period. Data were entered and calculations were done in Microsoft Excel, point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. RESULTS: Out of arterial blood gas analysis of 1144 patients, the prevalence of acid base disorders was 718 (62.76%) at 95% Confidence Interval (59.96-65.56%). Simple and mixed acid base disorders were observed in 332 (46.24%) and 386 (53.76%) patients respectively. Respiratory alkalosis was most common among 134 (40.36%) cases in simple acid base disorder whereas metabolic acidosis and respiratory alkalosis was most common among 204 (52.85%) in mixed acid base disorder. All types of disorders were observed more in elderly people (41-60 and >60 age group) than other age groups. CONCLUSIONS: Acid base disorder was found to be more common in very ill patients in emergency and intensive care units. Mixed acid base disorder was the most common with male and elderly patients in predominance. Journal of the Nepal Medical Association 2019 2019-12-31 /pmc/articles/PMC7580413/ /pubmed/32335656 http://dx.doi.org/10.31729/jnma.4722 Text en © The Author(s) 2018. http://creativecommons.org/licenses/by/4.0/ This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Shreewastav, Rupesh Kumar
Jaishi, Krishna Prasad
Pandey, Madan Raj
Singh, Ganesh Prasad
Singh, Arambam Giridhari
Study of Acid-Base Disorders and Biochemical Findings of Patients in a Tertiary Care Hospital: A Descriptive Cross-sectional Study
title Study of Acid-Base Disorders and Biochemical Findings of Patients in a Tertiary Care Hospital: A Descriptive Cross-sectional Study
title_full Study of Acid-Base Disorders and Biochemical Findings of Patients in a Tertiary Care Hospital: A Descriptive Cross-sectional Study
title_fullStr Study of Acid-Base Disorders and Biochemical Findings of Patients in a Tertiary Care Hospital: A Descriptive Cross-sectional Study
title_full_unstemmed Study of Acid-Base Disorders and Biochemical Findings of Patients in a Tertiary Care Hospital: A Descriptive Cross-sectional Study
title_short Study of Acid-Base Disorders and Biochemical Findings of Patients in a Tertiary Care Hospital: A Descriptive Cross-sectional Study
title_sort study of acid-base disorders and biochemical findings of patients in a tertiary care hospital: a descriptive cross-sectional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580413/
https://www.ncbi.nlm.nih.gov/pubmed/32335656
http://dx.doi.org/10.31729/jnma.4722
work_keys_str_mv AT shreewastavrupeshkumar studyofacidbasedisordersandbiochemicalfindingsofpatientsinatertiarycarehospitaladescriptivecrosssectionalstudy
AT jaishikrishnaprasad studyofacidbasedisordersandbiochemicalfindingsofpatientsinatertiarycarehospitaladescriptivecrosssectionalstudy
AT pandeymadanraj studyofacidbasedisordersandbiochemicalfindingsofpatientsinatertiarycarehospitaladescriptivecrosssectionalstudy
AT singhganeshprasad studyofacidbasedisordersandbiochemicalfindingsofpatientsinatertiarycarehospitaladescriptivecrosssectionalstudy
AT singharambamgiridhari studyofacidbasedisordersandbiochemicalfindingsofpatientsinatertiarycarehospitaladescriptivecrosssectionalstudy