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Thyrotoxic Periodic Paralysis with Hypokalemia in an Adult Male from Nepal: A Case Report

Thyrotoxic periodic paralysis is a rare complication of hyperthyroidism characterized by the sudden onset of hypokalemia and muscle paralysis. It is typically present in young Asian males. There are very few literatures regarding the occurrence of thyrotoxic hypokalemic periodic paralysis in Nepal....

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Autores principales: Khadka, Sabina, K.C., Indu, Rayamajhi, Rabindra Jang, Dawadi, Pravakar, Budhathoki, Pravash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580425/
https://www.ncbi.nlm.nih.gov/pubmed/32335663
http://dx.doi.org/10.31729/jnma.4763
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author Khadka, Sabina
K.C., Indu
Rayamajhi, Rabindra Jang
Dawadi, Pravakar
Budhathoki, Pravash
author_facet Khadka, Sabina
K.C., Indu
Rayamajhi, Rabindra Jang
Dawadi, Pravakar
Budhathoki, Pravash
author_sort Khadka, Sabina
collection PubMed
description Thyrotoxic periodic paralysis is a rare complication of hyperthyroidism characterized by the sudden onset of hypokalemia and muscle paralysis. It is typically present in young Asian males. There are very few literatures regarding the occurrence of thyrotoxic hypokalemic periodic paralysis in Nepal. We reported a case of a 35-year-old male presented with the chief complaints of weakness of all four limbs of 1 day duration. He was diagnosed as a case of hyperthyroidism in the past, received treatment for 6 months and left medications on his own 6 months ago. Evaluation during admission revealed severe hypokalemia with serum potassium level 1.3mEq/l and high serum Triiodothyronine (>20.00μ/L) and low serum Thyroid Stimulating Hormone (<0.01μ/L). Potassium supplements resolved muscle weakness and the patient was restarted with anti-thyroid drugs. Hence, hypokalemic paralysis is a reversible cause of paralysis and high index of suspicion as well as timely interventions are required to prevent potential harm.
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spelling pubmed-75804252020-11-30 Thyrotoxic Periodic Paralysis with Hypokalemia in an Adult Male from Nepal: A Case Report Khadka, Sabina K.C., Indu Rayamajhi, Rabindra Jang Dawadi, Pravakar Budhathoki, Pravash JNMA J Nepal Med Assoc Case Report Thyrotoxic periodic paralysis is a rare complication of hyperthyroidism characterized by the sudden onset of hypokalemia and muscle paralysis. It is typically present in young Asian males. There are very few literatures regarding the occurrence of thyrotoxic hypokalemic periodic paralysis in Nepal. We reported a case of a 35-year-old male presented with the chief complaints of weakness of all four limbs of 1 day duration. He was diagnosed as a case of hyperthyroidism in the past, received treatment for 6 months and left medications on his own 6 months ago. Evaluation during admission revealed severe hypokalemia with serum potassium level 1.3mEq/l and high serum Triiodothyronine (>20.00μ/L) and low serum Thyroid Stimulating Hormone (<0.01μ/L). Potassium supplements resolved muscle weakness and the patient was restarted with anti-thyroid drugs. Hence, hypokalemic paralysis is a reversible cause of paralysis and high index of suspicion as well as timely interventions are required to prevent potential harm. Journal of the Nepal Medical Association 2019 2019-12-31 /pmc/articles/PMC7580425/ /pubmed/32335663 http://dx.doi.org/10.31729/jnma.4763 Text en © The Author(s) 2018. http://creativecommons.org/licenses/by/4.0/ This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Khadka, Sabina
K.C., Indu
Rayamajhi, Rabindra Jang
Dawadi, Pravakar
Budhathoki, Pravash
Thyrotoxic Periodic Paralysis with Hypokalemia in an Adult Male from Nepal: A Case Report
title Thyrotoxic Periodic Paralysis with Hypokalemia in an Adult Male from Nepal: A Case Report
title_full Thyrotoxic Periodic Paralysis with Hypokalemia in an Adult Male from Nepal: A Case Report
title_fullStr Thyrotoxic Periodic Paralysis with Hypokalemia in an Adult Male from Nepal: A Case Report
title_full_unstemmed Thyrotoxic Periodic Paralysis with Hypokalemia in an Adult Male from Nepal: A Case Report
title_short Thyrotoxic Periodic Paralysis with Hypokalemia in an Adult Male from Nepal: A Case Report
title_sort thyrotoxic periodic paralysis with hypokalemia in an adult male from nepal: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580425/
https://www.ncbi.nlm.nih.gov/pubmed/32335663
http://dx.doi.org/10.31729/jnma.4763
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