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Thyroid Storm Presenting as Septic Shock in the Intensive Care Unit: A Case Series

Thyroid storm is a rare endocrine emergency that rarely presents with septic shock. It occurs in thyrotoxic patients and is manifested by decompensation of multiple organs, triggered by severe stress. The diagnosis and response to treatment is made by Burch-Wartofsky point scale or Japanese thyroid...

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Autores principales: Keyai, Niraj Kumar, Nepal, Niru, Khanal, Sudesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580483/
https://www.ncbi.nlm.nih.gov/pubmed/32335640
http://dx.doi.org/10.31729/jnma.4552
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author Keyai, Niraj Kumar
Nepal, Niru
Khanal, Sudesh
author_facet Keyai, Niraj Kumar
Nepal, Niru
Khanal, Sudesh
author_sort Keyai, Niraj Kumar
collection PubMed
description Thyroid storm is a rare endocrine emergency that rarely presents with septic shock. It occurs in thyrotoxic patients and is manifested by decompensation of multiple organs, triggered by severe stress. The diagnosis and response to treatment is made by Burch-Wartofsky point scale or Japanese thyroid association criteria due to lack of pathophysiology of thyroid storm. We reported series of patients that presented with altered sensorium, cough, fever, palpitation, shortness of breath and shock. Patient were treated initially for septic shock, later diagnosed as thyroid storm and was treated with oral carbimazole, propanolol and digoxin. From this, we want to emphasize that thyroid storm can have any presentation that should be kept in differential diagnosis of septic shock not responding to usual treatment; early diagnosis and treatment with oral medication can decrease morbidity and mortality in rural setting where intravenous form of antithyroid drug are not available for thyroid storm.
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spelling pubmed-75804832020-11-30 Thyroid Storm Presenting as Septic Shock in the Intensive Care Unit: A Case Series Keyai, Niraj Kumar Nepal, Niru Khanal, Sudesh JNMA J Nepal Med Assoc Case Report Thyroid storm is a rare endocrine emergency that rarely presents with septic shock. It occurs in thyrotoxic patients and is manifested by decompensation of multiple organs, triggered by severe stress. The diagnosis and response to treatment is made by Burch-Wartofsky point scale or Japanese thyroid association criteria due to lack of pathophysiology of thyroid storm. We reported series of patients that presented with altered sensorium, cough, fever, palpitation, shortness of breath and shock. Patient were treated initially for septic shock, later diagnosed as thyroid storm and was treated with oral carbimazole, propanolol and digoxin. From this, we want to emphasize that thyroid storm can have any presentation that should be kept in differential diagnosis of septic shock not responding to usual treatment; early diagnosis and treatment with oral medication can decrease morbidity and mortality in rural setting where intravenous form of antithyroid drug are not available for thyroid storm. Journal of the Nepal Medical Association 2020-01 2020-01-31 /pmc/articles/PMC7580483/ /pubmed/32335640 http://dx.doi.org/10.31729/jnma.4552 Text en © The Author(s) 2018. http://creativecommons.org/licenses/by/4.0/ This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Keyai, Niraj Kumar
Nepal, Niru
Khanal, Sudesh
Thyroid Storm Presenting as Septic Shock in the Intensive Care Unit: A Case Series
title Thyroid Storm Presenting as Septic Shock in the Intensive Care Unit: A Case Series
title_full Thyroid Storm Presenting as Septic Shock in the Intensive Care Unit: A Case Series
title_fullStr Thyroid Storm Presenting as Septic Shock in the Intensive Care Unit: A Case Series
title_full_unstemmed Thyroid Storm Presenting as Septic Shock in the Intensive Care Unit: A Case Series
title_short Thyroid Storm Presenting as Septic Shock in the Intensive Care Unit: A Case Series
title_sort thyroid storm presenting as septic shock in the intensive care unit: a case series
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580483/
https://www.ncbi.nlm.nih.gov/pubmed/32335640
http://dx.doi.org/10.31729/jnma.4552
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