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Innate and adaptive immune responses against coronavirus

Coronaviruses (CoVs) are a member of the Coronaviridae family with positive‐sense single- stranded RNA. In recent years, the CoVs have become a global problem to public health. The immune responses (innate and adaptive immunity) are essential for elimination and clearance of CoVs infections, however...

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Autores principales: Hosseini, Arezoo, Hashemi, Vida, Shomali, Navid, Asghari, Faezeh, Gharibi, Tohid, Akbari, Morteza, Gholizadeh, Saber, Jafari, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580677/
https://www.ncbi.nlm.nih.gov/pubmed/33120236
http://dx.doi.org/10.1016/j.biopha.2020.110859
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author Hosseini, Arezoo
Hashemi, Vida
Shomali, Navid
Asghari, Faezeh
Gharibi, Tohid
Akbari, Morteza
Gholizadeh, Saber
Jafari, Abbas
author_facet Hosseini, Arezoo
Hashemi, Vida
Shomali, Navid
Asghari, Faezeh
Gharibi, Tohid
Akbari, Morteza
Gholizadeh, Saber
Jafari, Abbas
author_sort Hosseini, Arezoo
collection PubMed
description Coronaviruses (CoVs) are a member of the Coronaviridae family with positive‐sense single- stranded RNA. In recent years, the CoVs have become a global problem to public health. The immune responses (innate and adaptive immunity) are essential for elimination and clearance of CoVs infections, however, uncontrolled immune responses can result in aggravating acute lung injury and significant immunopathology. Gaining profound understanding about the interaction between CoVs and the innate and adaptive immune systems could be a critical step in the field of treatment. In this review, we present an update on the host innate and adaptive immune responses against SARS-CoV, MERS-CoV and newly appeared SARS-CoV-2.
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spelling pubmed-75806772020-10-23 Innate and adaptive immune responses against coronavirus Hosseini, Arezoo Hashemi, Vida Shomali, Navid Asghari, Faezeh Gharibi, Tohid Akbari, Morteza Gholizadeh, Saber Jafari, Abbas Biomed Pharmacother Review Coronaviruses (CoVs) are a member of the Coronaviridae family with positive‐sense single- stranded RNA. In recent years, the CoVs have become a global problem to public health. The immune responses (innate and adaptive immunity) are essential for elimination and clearance of CoVs infections, however, uncontrolled immune responses can result in aggravating acute lung injury and significant immunopathology. Gaining profound understanding about the interaction between CoVs and the innate and adaptive immune systems could be a critical step in the field of treatment. In this review, we present an update on the host innate and adaptive immune responses against SARS-CoV, MERS-CoV and newly appeared SARS-CoV-2. The Author(s). Published by Elsevier Masson SAS. 2020-12 2020-10-22 /pmc/articles/PMC7580677/ /pubmed/33120236 http://dx.doi.org/10.1016/j.biopha.2020.110859 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Hosseini, Arezoo
Hashemi, Vida
Shomali, Navid
Asghari, Faezeh
Gharibi, Tohid
Akbari, Morteza
Gholizadeh, Saber
Jafari, Abbas
Innate and adaptive immune responses against coronavirus
title Innate and adaptive immune responses against coronavirus
title_full Innate and adaptive immune responses against coronavirus
title_fullStr Innate and adaptive immune responses against coronavirus
title_full_unstemmed Innate and adaptive immune responses against coronavirus
title_short Innate and adaptive immune responses against coronavirus
title_sort innate and adaptive immune responses against coronavirus
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580677/
https://www.ncbi.nlm.nih.gov/pubmed/33120236
http://dx.doi.org/10.1016/j.biopha.2020.110859
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