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Innate and adaptive immune responses against coronavirus
Coronaviruses (CoVs) are a member of the Coronaviridae family with positive‐sense single- stranded RNA. In recent years, the CoVs have become a global problem to public health. The immune responses (innate and adaptive immunity) are essential for elimination and clearance of CoVs infections, however...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Masson SAS.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580677/ https://www.ncbi.nlm.nih.gov/pubmed/33120236 http://dx.doi.org/10.1016/j.biopha.2020.110859 |
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author | Hosseini, Arezoo Hashemi, Vida Shomali, Navid Asghari, Faezeh Gharibi, Tohid Akbari, Morteza Gholizadeh, Saber Jafari, Abbas |
author_facet | Hosseini, Arezoo Hashemi, Vida Shomali, Navid Asghari, Faezeh Gharibi, Tohid Akbari, Morteza Gholizadeh, Saber Jafari, Abbas |
author_sort | Hosseini, Arezoo |
collection | PubMed |
description | Coronaviruses (CoVs) are a member of the Coronaviridae family with positive‐sense single- stranded RNA. In recent years, the CoVs have become a global problem to public health. The immune responses (innate and adaptive immunity) are essential for elimination and clearance of CoVs infections, however, uncontrolled immune responses can result in aggravating acute lung injury and significant immunopathology. Gaining profound understanding about the interaction between CoVs and the innate and adaptive immune systems could be a critical step in the field of treatment. In this review, we present an update on the host innate and adaptive immune responses against SARS-CoV, MERS-CoV and newly appeared SARS-CoV-2. |
format | Online Article Text |
id | pubmed-7580677 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Author(s). Published by Elsevier Masson SAS. |
record_format | MEDLINE/PubMed |
spelling | pubmed-75806772020-10-23 Innate and adaptive immune responses against coronavirus Hosseini, Arezoo Hashemi, Vida Shomali, Navid Asghari, Faezeh Gharibi, Tohid Akbari, Morteza Gholizadeh, Saber Jafari, Abbas Biomed Pharmacother Review Coronaviruses (CoVs) are a member of the Coronaviridae family with positive‐sense single- stranded RNA. In recent years, the CoVs have become a global problem to public health. The immune responses (innate and adaptive immunity) are essential for elimination and clearance of CoVs infections, however, uncontrolled immune responses can result in aggravating acute lung injury and significant immunopathology. Gaining profound understanding about the interaction between CoVs and the innate and adaptive immune systems could be a critical step in the field of treatment. In this review, we present an update on the host innate and adaptive immune responses against SARS-CoV, MERS-CoV and newly appeared SARS-CoV-2. The Author(s). Published by Elsevier Masson SAS. 2020-12 2020-10-22 /pmc/articles/PMC7580677/ /pubmed/33120236 http://dx.doi.org/10.1016/j.biopha.2020.110859 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Review Hosseini, Arezoo Hashemi, Vida Shomali, Navid Asghari, Faezeh Gharibi, Tohid Akbari, Morteza Gholizadeh, Saber Jafari, Abbas Innate and adaptive immune responses against coronavirus |
title | Innate and adaptive immune responses against coronavirus |
title_full | Innate and adaptive immune responses against coronavirus |
title_fullStr | Innate and adaptive immune responses against coronavirus |
title_full_unstemmed | Innate and adaptive immune responses against coronavirus |
title_short | Innate and adaptive immune responses against coronavirus |
title_sort | innate and adaptive immune responses against coronavirus |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580677/ https://www.ncbi.nlm.nih.gov/pubmed/33120236 http://dx.doi.org/10.1016/j.biopha.2020.110859 |
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