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Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis
The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580746/ https://www.ncbi.nlm.nih.gov/pubmed/33110301 http://dx.doi.org/10.4103/ccd.ccd_448_19 |
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author | Sasikumar, P. K. Varghese, Sheeja S Kumaran, Thanga Devi, Sakthi Saranya |
author_facet | Sasikumar, P. K. Varghese, Sheeja S Kumaran, Thanga Devi, Sakthi Saranya |
author_sort | Sasikumar, P. K. |
collection | PubMed |
description | The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis. |
format | Online Article Text |
id | pubmed-7580746 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-75807462020-10-26 Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis Sasikumar, P. K. Varghese, Sheeja S Kumaran, Thanga Devi, Sakthi Saranya Contemp Clin Dent Review Article The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis. Wolters Kluwer - Medknow 2020 2020-07-13 /pmc/articles/PMC7580746/ /pubmed/33110301 http://dx.doi.org/10.4103/ccd.ccd_448_19 Text en Copyright: © 2020 Contemporary Clinical Dentistry http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Sasikumar, P. K. Varghese, Sheeja S Kumaran, Thanga Devi, Sakthi Saranya Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis |
title | Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis |
title_full | Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis |
title_fullStr | Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis |
title_full_unstemmed | Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis |
title_short | Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis |
title_sort | meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580746/ https://www.ncbi.nlm.nih.gov/pubmed/33110301 http://dx.doi.org/10.4103/ccd.ccd_448_19 |
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