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Use of complete clearance for assessing treatment efficacy for 5-fluorouracil interventions in actinic keratoses: how baseline lesion count can impact this outcome

Background: Many trials in actinic keratoses (AK) use complete clearance rate (100% reduction in number of lesions) as the primary endpoint. We explore limitations (predominantly baseline factors) associated with this outcome. Objective: This analysis assessed the effect of baseline lesion count on...

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Detalles Bibliográficos
Autores principales: Ezzedine, Khaled, Painchault, Caroline, Brignone, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Routledge 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580760/
https://www.ncbi.nlm.nih.gov/pubmed/33133432
http://dx.doi.org/10.1080/20016689.2020.1829884