Zinc and COVID-19: Basis of Current Clinical Trials

Coronavirus disease-2019 (COVID-19) pandemic continues to threaten patients, societies, and economic and healthcare systems around the world. Like many other diseases, the host immune system determines the progress of COVID-19 and fatality. Modulation of inflammatory response and cytokine production...

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Detalles Bibliográficos
Autores principales: Pal, Amit, Squitti, Rosanna, Picozza, Mario, Pawar, Anil, Rongioletti, Mauro, Dutta, Atanu Kumar, Sahoo, Sibasish, Goswami, Kalyan, Sharma, Praveen, Prasad, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580816/
https://www.ncbi.nlm.nih.gov/pubmed/33094446
http://dx.doi.org/10.1007/s12011-020-02437-9
Descripción
Sumario:Coronavirus disease-2019 (COVID-19) pandemic continues to threaten patients, societies, and economic and healthcare systems around the world. Like many other diseases, the host immune system determines the progress of COVID-19 and fatality. Modulation of inflammatory response and cytokine production using immunonutrition is a novel concept that has been applied to other diseases as well. Zinc, one of the anti-inflammatory and antioxidant micronutrient found in food with well-established role in immunity, is currently being used in some clinical trials against COVID-19. This review integrates the contemporary studies of role of zinc in antiviral immunity along with discussing its potential role against COVID-19, and ongoing COVID-19 clinical trials using zinc.

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