Cargando…
Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer
Evidence has been accumulating to indicate that extracellular vesicles (EVs), including exosomes, released by cancer cells can foster tumour progression. The molecular chaperones – CDC37, HSP90α and HSP90β play key roles in cancer progression including epithelial-mesenchymal transition (EMT), althou...
Autores principales: | Ono, Kisho, Sogawa, Chiharu, Kawai, Hotaka, Tran, Manh Tien, Taha, Eman A., Lu, Yanyin, Oo, May Wathone, Okusha, Yuka, Okamura, Hirohiko, Ibaragi, Soichiro, Takigawa, Masaharu, Kozaki, Ken-Ichi, Nagatsuka, Hitoshi, Sasaki, Akira, Okamoto, Kuniaki, Calderwood, Stuart K., Eguchi, Takanori |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580842/ https://www.ncbi.nlm.nih.gov/pubmed/33144925 http://dx.doi.org/10.1080/20013078.2020.1769373 |
Ejemplares similares
-
Cell Stress Induced Stressome Release Including Damaged Membrane Vesicles and Extracellular HSP90 by Prostate Cancer Cells
por: Eguchi, Takanori, et al.
Publicado: (2020) -
Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment
por: Eguchi, Takanori, et al.
Publicado: (2018) -
Knockout of MMP3 Weakens Solid Tumor Organoids and Cancer Extracellular Vesicles
por: Taha, Eman A., et al.
Publicado: (2020) -
Antiparkinson Drug Benztropine Suppresses Tumor Growth, Circulating Tumor Cells, and Metastasis by Acting on SLC6A3/DAT and Reducing STAT3
por: Sogawa, Chiharu, et al.
Publicado: (2020) -
Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer
por: Okusha, Yuka, et al.
Publicado: (2020)