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The future of Extracellular Vesicles as Theranostics – an ISEV meeting report

The utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in the past decade. In November 2018, the International Society for Extracellular Vesicles (ISEV) held a workshop on “EVs in Clinical Theranostic”. Here, we report the conclusions of roundtable discussions...

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Detalles Bibliográficos
Autores principales: Soekmadji, Carolina, Li, Bo, Huang, Yiyao, Wang, Haifang, An, Taixue, Liu, Chunchen, Pan, Weilun, Chen, Jing, Cheung, Lesley, Falcon-Perez, Juan Manuel, Gho, Yong Song, Holthofer, Harry B., Le, Minh T. N., Marcilla, Antonio, O’Driscoll, Lorraine, Shekari, Faezeh, Shen, Tang Long, Torrecilhas, Ana Claudia, Yan, Xiaomei, Yang, Fuquan, Yin, Hang, Xiao, Yu, Zhao, Zezhou, Zou, Xue, Wang, Qian, Zheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580849/
https://www.ncbi.nlm.nih.gov/pubmed/33144926
http://dx.doi.org/10.1080/20013078.2020.1809766
Descripción
Sumario:The utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in the past decade. In November 2018, the International Society for Extracellular Vesicles (ISEV) held a workshop on “EVs in Clinical Theranostic”. Here, we report the conclusions of roundtable discussions on the current advancement in the analysis technologies and we provide some guidelines to researchers in the field to consider the use of EVs in clinical application. The main challenges and the requirements for EV separation and characterization strategies, quality control and clinical investigation were discussed to promote the application of EVs in future clinical studies.