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Minimal structural elements required for midline repulsive signaling and regulation of Drosophila Robo1

The Roundabout (Robo) family of axon guidance receptors has a conserved ectodomain arrangement of five immunoglobulin-like (Ig) domains plus three fibronectin type III (Fn) repeats. Based on the strong evolutionary conservation of this domain structure among Robo receptors, as well as in vitro struc...

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Detalles Bibliográficos
Autores principales: Brown, Haley E., Evans, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580999/
https://www.ncbi.nlm.nih.gov/pubmed/33091076
http://dx.doi.org/10.1371/journal.pone.0241150

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