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Protein-Directed Dynamic Combinatorial Chemistry: An Efficient Strategy in Drug Design
[Image: see text] Protein-directed dynamic combinatorial chemistry (P-D DCC) is considered a powerful strategy to identify ligands to pharmacologically relevant protein targets. The protein selects its affinity ligands in situ through a thermodynamic templated effect in which the library composition...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581073/ https://www.ncbi.nlm.nih.gov/pubmed/33110958 http://dx.doi.org/10.1021/acsomega.0c03800 |