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Efficacy of afatinib for pulmonary adenocarcinoma with leptomeningeal metastases harboring an epidermal growth factor receptor complex mutation (exon 19del+K754E): A case report

RATIONALE: Liquid biopsy of cerebrospinal fluid (CSF) and sequencing of cell-free DNA has rarely been used to identify epidermal growth factor receptor (EGFR) mutations, which can guide the design of precise, personalized treatment for patients with leptomeningeal metastasis from lung adenocarcinoma...

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Detalles Bibliográficos
Autores principales:	Ma, Chunhua, Liu, Mei, Mu, Ning, Li, Jinduo, Li, Lin, Jiang, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	5700
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581162/ https://www.ncbi.nlm.nih.gov/pubmed/33120820 http://dx.doi.org/10.1097/MD.0000000000022851

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