Introducing polymer conductance in diagnostically relevant transduction

In this work we demonstrate that an impedance derived capacitance method is able to cleanly resolve the resonant conductance characteristics of an electrode-confined polymer film. In decorating the film with receptors, this conductance is thereafter modulated by the capturing of specific targets, demonstrated herein with C-reactive protein. This entirely reagentless and single step marker quantification is relevant to the drive of moving assays to a scaleable format requiring minimal user intervention.