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Feedback control of Wnt signaling based on ultrastable histidine cluster co-aggregation between Naked/NKD and Axin

Feedback control is a universal feature of cell signaling pathways. Naked/NKD is a widely conserved feedback regulator of Wnt signaling which controls animal development and tissue homeostasis. Naked/NKD destabilizes Dishevelled, which assembles Wnt signalosomes to inhibit the β-catenin destruction...

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Detalles Bibliográficos
Autores principales:	Gammons, Melissa V, Renko, Miha, Flack, Joshua E, Mieszczanek, Juliusz, Bienz, Mariann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581431/ https://www.ncbi.nlm.nih.gov/pubmed/33025907 http://dx.doi.org/10.7554/eLife.59879

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