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Challenges in Detecting Clinically Relevant Heparin-Induced Thrombocytopenia Antibodies
Heparin-induced thrombocytopenia (HIT) is an antibody-mediated hypercoagulable state featuring high thrombosis risk and distinct pathogenesis involving immunoglobulin G-mediated platelet activation. The target of the immune response is a cationic “self” protein, platelet factor 4 (PF4), rendered ant...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Georg Thieme Verlag KG
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581458/ https://www.ncbi.nlm.nih.gov/pubmed/33091948 http://dx.doi.org/10.1055/a-1223-3329 |