FGF18–FGFR2 signaling triggers the activation of c-Jun–YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential

Fibroblast growth factor receptor type 2 (FGFR2) has emerged as a key oncogenic factor that regulates gastric cancer (GC) progression, but the underlying mechanism of FGF–FGFR2 signaling pathway remains largely unknown. To identify the potential molecular mechanisms of the oncogenic FGFR2 in gastric...

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Detalles Bibliográficos
Autores principales: Zhang, Jinglin, Wong, Chi Chun, Leung, Kam Tong, Wu, Feng, Zhou, Yuhang, Tong, Joanna H. M., Chan, Ronald C. K., Li, Hui, Wang, Yifei, Yan, Huan, Liu, Liping, Wu, William K. K., Chan, Michael W. Y., Cheng, Alfred S. L., Yu, Jun, Wong, Nathalie, Lo, Kwok Wai, To, Ka Fai, Kang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581496/
https://www.ncbi.nlm.nih.gov/pubmed/32934314
http://dx.doi.org/10.1038/s41388-020-01458-x

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