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Epigenetic Cell Fate in Candida albicans is Controlled by Transcription Factor Condensates Acting at Super-Enhancer-Like Elements

Cell identity in eukaryotes is controlled by transcriptional regulatory networks (TRNs) that define cell type-specific gene expression. In the opportunistic fungal pathogen Candida albicans, TRNs regulate epigenetic switching between two alternative cell states, ‘white’ and ‘opaque’, that exhibit di...

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Detalles Bibliográficos
Autores principales: Frazer, Corey, Staples, Mae I., Kim, Yoori, Hirakawa, Matthew, Dowell, Maureen A., Johnson, Nicole V., Hernday, Aaron D., Ryan, Veronica H., Fawzi, Nicolas L., Finkelstein, Ilya J., Bennett, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581547/
https://www.ncbi.nlm.nih.gov/pubmed/32719507
http://dx.doi.org/10.1038/s41564-020-0760-7