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Metabolic Perturbations Caused by the Over-Expression of mcr-1 in Escherichia coli

Rapid dissemination of the plasmid-born polymyxin resistance gene mcr-1 poses a critical medical challenge. MCR-1 expression is tightly controlled and imposes a fitness cost on the bacteria. We used growth studies and metabolomics to examine growth and metabolic changes within E. coli TOP10 at 8 and...

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Detalles Bibliográficos
Autores principales:	Liu, Yi-Yun, Zhu, Yan, Wickremasinghe, Hasini, Bergen, Phillip J., Lu, Jing, Zhu, Xiao-Qing, Zhou, Qiao-Li, Azad, Mohammad, Nang, Sue C., Han, Mei-Ling, Lei, Tao, Li, Jian, Liu, Jian-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581681/ https://www.ncbi.nlm.nih.gov/pubmed/33162965 http://dx.doi.org/10.3389/fmicb.2020.588658

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