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Sapitinib Reverses Anticancer Drug Resistance in Colon Cancer Cells Overexpressing the ABCB1 Transporter
The efficacy of anti-cancer drugs in patients can be attenuated by the development of multi-drug resistance (MDR) due to ATP-binding cassette (ABC) transporters overexpression. In this in vitro study, we determined the reversal efficacy of the epidermal growth factor receptor (EFGR) inhibitor, sapti...
Autores principales: | Gao, Hai-Ling, Gupta, Pranav, Cui, Qingbin, Ashar, Yunali V., Wu, Zhuo-Xun, Zeng, Leli, Lei, Zi-Ning, Teng, Qiu-Xu, Ashby, Charles R., Guan, Yingjun, Chen, Zhe-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581728/ https://www.ncbi.nlm.nih.gov/pubmed/33163405 http://dx.doi.org/10.3389/fonc.2020.574861 |
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