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Antileukemic activity of the VPS34-IN1 inhibitor in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive disease with a poor prognosis. Vacuolar protein sorting 34 (VPS34) is a member of the phosphatidylinositol-3-kinase lipid kinase family that controls the canonical autophagy pathway and vesicular trafficking. Using a recently developed specific inhibitor...

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Detalles Bibliográficos
Autores principales:	Meunier, Godelieve, Birsen, Rudy, Cazelles, Clarisse, Belhadj, Maya, Cantero-Aguilar, Lilia, Kosmider, Olivier, Fontenay, Michaela, Azar, Nabih, Mayeux, Patrick, Chapuis, Nicolas, Tamburini, Jerôme, Bouscary, Didier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581748/ https://www.ncbi.nlm.nih.gov/pubmed/33093450 http://dx.doi.org/10.1038/s41389-020-00278-8

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