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Adenosine and ATPγS protect against bacterial pneumonia-induced acute lung injury
Lipopolysaccharide (LPS), a component of the outer membrane of gram-negative bacteria, disrupts the alveolar-capillary barrier, triggering pulmonary vascular leak thus inducing acute lung injury (ALI). Extracellular purines, adenosine and ATP, protected against ALI induced by purified LPS. In this s...
Autores principales: | Gross, Christine M., Kovacs-Kasa, Anita, Meadows, Mary Louise, Cherian-Shaw, Mary, Fulton, David J., Verin, Alexander D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581771/ https://www.ncbi.nlm.nih.gov/pubmed/33093565 http://dx.doi.org/10.1038/s41598-020-75224-0 |
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