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Chronic bryostatin-1 rescues autistic and cognitive phenotypes in the fragile X mice
Fragile X syndrome (FXS), an X-chromosome linked intellectual disability, is the leading monogenetic cause of autism spectrum disorder (ASD), a neurodevelopmental condition that currently has no specific drug treatment. Building upon the demonstrated therapeutic effects on spatial memory of bryostat...
Autores principales: | Cogram, Patricia, Alkon, Daniel L., Crockford, David, Deacon, Robert M. J., Hurley, Michael J., Altimiras, Francisco, Sun, Miao-Kun, Tranfaglia, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581799/ https://www.ncbi.nlm.nih.gov/pubmed/33093534 http://dx.doi.org/10.1038/s41598-020-74848-6 |
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