Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis

The aim of the present study was to investigate the neuroprotective roles and mechanisms of the circular RNA circSHOC2 in ischemic-preconditioned astrocyte-derived exosomes (IPAS-EXOs) against ischemic stroke. We established an ischemia model based on oxygen glucose deprivation (OGD) in vitro and is...

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Detalles Bibliográficos
Autores principales: Chen, Wanghao, Wang, Hong, Zhu, Zhihan, Feng, Jia, Chen, Lukui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581834/
https://www.ncbi.nlm.nih.gov/pubmed/33230464
http://dx.doi.org/10.1016/j.omtn.2020.09.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581834/
https://www.ncbi.nlm.nih.gov/pubmed/33230464
http://dx.doi.org/10.1016/j.omtn.2020.09.027

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