Epistatic evidence for gender-dependant slow neurotransmission signalling in substance use disorders: PPP1R12B versus PPP1R1B

BACKGROUND: Slow neurotransmission including DARPP-32 signalling is implicated in substance use disorders (SUDs) by experimental systems but not yet in the human aetiology. PPP1R12B, encoding another protein in the DARPP-32 family, hasn't been studied in the brain. METHODS: Brain-regional gene...

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Detalles Bibliográficos
Autores principales: Liu, Kefu, Zhao, Juan, Chen, Chunnuan, Xu, Jie, Bell, Richard L., Hall, Frank S., Koob, George F., Volkow, Nora D., Qing, Hong, Lin, Zhicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581882/
https://www.ncbi.nlm.nih.gov/pubmed/33096475
http://dx.doi.org/10.1016/j.ebiom.2020.103066

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