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Loss of the Extracellular Matrix Molecule Tenascin-C Leads to Absence of Reactive Gliosis and Promotes Anti-inflammatory Cytokine Expression in an Autoimmune Glaucoma Mouse Model

Previous studies demonstrated that retinal damage correlates with a massive remodeling of extracellular matrix (ECM) molecules and reactive gliosis. However, the functional significance of the ECM in retinal neurodegeneration is still unknown. In the present study, we used an intraocular pressure (I...

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Detalles Bibliográficos
Autores principales: Wiemann, Susanne, Reinhard, Jacqueline, Reinehr, Sabrina, Cibir, Zülal, Joachim, Stephanie C., Faissner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581917/
https://www.ncbi.nlm.nih.gov/pubmed/33162981
http://dx.doi.org/10.3389/fimmu.2020.566279

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