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Tumor Phylogeny Topology Inference via Deep Learning
Principled computational approaches for tumor phylogeny reconstruction via single-cell sequencing typically aim to build the most likely perfect phylogeny tree from the noisy genotype matrix – which represents genotype calls of single cells. This problem is NP-hard, and as a result, existing approac...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582044/ https://www.ncbi.nlm.nih.gov/pubmed/33117968 http://dx.doi.org/10.1016/j.isci.2020.101655 |