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Effect of Electroacupuncture on Pain Perception and Pain-Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1
Electroacupuncture (EA) can effectively modulate pain perception and pain-related negative affect; however, we do not know whether the effect of EA on sensation and affect is parallel, or dissociated, interactional. In this study, we observed the effects of the anterior cingulate cortex (ACC) lesion...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582085/ https://www.ncbi.nlm.nih.gov/pubmed/33123189 http://dx.doi.org/10.1155/2020/8865096 |
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author | Shi, Yan Yao, Shujing Shen, Zui She, Lijiao Xu, Yingling Liu, Boyi Liang, Yi Jiang, Yongliang Sun, Jing Wu, Yuanyuan Du, Junying Zhu, Yilin Wu, Zemin Fang, Jianqiao Shao, Xiaomei |
author_facet | Shi, Yan Yao, Shujing Shen, Zui She, Lijiao Xu, Yingling Liu, Boyi Liang, Yi Jiang, Yongliang Sun, Jing Wu, Yuanyuan Du, Junying Zhu, Yilin Wu, Zemin Fang, Jianqiao Shao, Xiaomei |
author_sort | Shi, Yan |
collection | PubMed |
description | Electroacupuncture (EA) can effectively modulate pain perception and pain-related negative affect; however, we do not know whether the effect of EA on sensation and affect is parallel, or dissociated, interactional. In this study, we observed the effects of the anterior cingulate cortex (ACC) lesion and the primary somatosensory cortex (S1) activation on pain perception, pain-related affection, and neural oscillation in S1. ACC lesions did not affect pain perception but relieved pain-paired aversion. S1 activation increased pain perception and anxious behavior. EA can mitigate pain perception regardless of whether there is an ACC lesion. Chronic pain may increase the delta and theta band oscillatory activity in the S1 brain region and decrease the oscillatory activity in the alpha, beta, and gamma bands. EA intervention may inhibit the oscillatory activity of the alpha and beta bands. These results suggest that EA may mitigate chronic pain by relieving pain perception and reducing pain-related affection through different mechanisms. This evidence builds upon findings from previous studies of chronic pain and EA treatment. |
format | Online Article Text |
id | pubmed-7582085 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-75820852020-10-28 Effect of Electroacupuncture on Pain Perception and Pain-Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1 Shi, Yan Yao, Shujing Shen, Zui She, Lijiao Xu, Yingling Liu, Boyi Liang, Yi Jiang, Yongliang Sun, Jing Wu, Yuanyuan Du, Junying Zhu, Yilin Wu, Zemin Fang, Jianqiao Shao, Xiaomei Neural Plast Research Article Electroacupuncture (EA) can effectively modulate pain perception and pain-related negative affect; however, we do not know whether the effect of EA on sensation and affect is parallel, or dissociated, interactional. In this study, we observed the effects of the anterior cingulate cortex (ACC) lesion and the primary somatosensory cortex (S1) activation on pain perception, pain-related affection, and neural oscillation in S1. ACC lesions did not affect pain perception but relieved pain-paired aversion. S1 activation increased pain perception and anxious behavior. EA can mitigate pain perception regardless of whether there is an ACC lesion. Chronic pain may increase the delta and theta band oscillatory activity in the S1 brain region and decrease the oscillatory activity in the alpha, beta, and gamma bands. EA intervention may inhibit the oscillatory activity of the alpha and beta bands. These results suggest that EA may mitigate chronic pain by relieving pain perception and reducing pain-related affection through different mechanisms. This evidence builds upon findings from previous studies of chronic pain and EA treatment. Hindawi 2020-10-13 /pmc/articles/PMC7582085/ /pubmed/33123189 http://dx.doi.org/10.1155/2020/8865096 Text en Copyright © 2020 Yan Shi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Shi, Yan Yao, Shujing Shen, Zui She, Lijiao Xu, Yingling Liu, Boyi Liang, Yi Jiang, Yongliang Sun, Jing Wu, Yuanyuan Du, Junying Zhu, Yilin Wu, Zemin Fang, Jianqiao Shao, Xiaomei Effect of Electroacupuncture on Pain Perception and Pain-Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1 |
title | Effect of Electroacupuncture on Pain Perception and Pain-Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1 |
title_full | Effect of Electroacupuncture on Pain Perception and Pain-Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1 |
title_fullStr | Effect of Electroacupuncture on Pain Perception and Pain-Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1 |
title_full_unstemmed | Effect of Electroacupuncture on Pain Perception and Pain-Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1 |
title_short | Effect of Electroacupuncture on Pain Perception and Pain-Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1 |
title_sort | effect of electroacupuncture on pain perception and pain-related affection: dissociation or interaction based on the anterior cingulate cortex and s1 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582085/ https://www.ncbi.nlm.nih.gov/pubmed/33123189 http://dx.doi.org/10.1155/2020/8865096 |
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