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Altered IHH signaling contributes to reduced chondrocyte proliferation in the growth plate of MPS VII mice

Bone elongation is driven by chondrocyte proliferation and hypertrophy in the growth plate. Both processes are modulated by multiple signaling pathways including the Indian Hedgehog (IHH) signaling pathway. Mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders characterized by accum...

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Detalles Bibliográficos
Autores principales:	Jiang, Zhirui, Derrick-Roberts, Ainslie L.K., Byers, Sharon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582094/ https://www.ncbi.nlm.nih.gov/pubmed/33117654 http://dx.doi.org/10.1016/j.ymgmr.2020.100668

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