A miner with No left lung: Extensive pulmonary destruction in delayed effective Multi-Drug-Resistant Tuberculosis treatment

We report a case of extensive pulmonary destruction due to delayed effective pulmonary tuberculosis (TB) treatment in an adult artisanal miner in eastern Democratic Republic of Congo. Xpert MTB/RIF was positive after his second rifampicin-susceptible TB treatment. Chest X-rays were suggestive of lar...

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Autores principales: Katoto, Patrick D.M.C., Musole, Patrick, Maheshe, Ghislain, Bamuleke, Bertrand, Murhula, Aime, Balungwe, Patrick, Byamungu, Liliane N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582097/
https://www.ncbi.nlm.nih.gov/pubmed/33117645
http://dx.doi.org/10.1016/j.rmcr.2020.101234
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author Katoto, Patrick D.M.C.
Musole, Patrick
Maheshe, Ghislain
Bamuleke, Bertrand
Murhula, Aime
Balungwe, Patrick
Byamungu, Liliane N.
author_facet Katoto, Patrick D.M.C.
Musole, Patrick
Maheshe, Ghislain
Bamuleke, Bertrand
Murhula, Aime
Balungwe, Patrick
Byamungu, Liliane N.
author_sort Katoto, Patrick D.M.C.
collection PubMed
description We report a case of extensive pulmonary destruction due to delayed effective pulmonary tuberculosis (TB) treatment in an adult artisanal miner in eastern Democratic Republic of Congo. Xpert MTB/RIF was positive after his second rifampicin-susceptible TB treatment. Chest X-rays were suggestive of large cavity, fibrosis of remaining lung and air-fluid levels at the base of the destroyed lung. The patient passed away after delayed effective TB regimens. Clinicians should be aware that urgent surgical intervention is often required to prevent lethal acute respiratory failure and shock notwithstanding effective chemotherapy in such condition. Effort is needed to timely diagnose multidrug resistance TB and to implement thoracic surgery for TB in high burden countries.
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spelling pubmed-75820972020-10-27 A miner with No left lung: Extensive pulmonary destruction in delayed effective Multi-Drug-Resistant Tuberculosis treatment Katoto, Patrick D.M.C. Musole, Patrick Maheshe, Ghislain Bamuleke, Bertrand Murhula, Aime Balungwe, Patrick Byamungu, Liliane N. Respir Med Case Rep Case Report We report a case of extensive pulmonary destruction due to delayed effective pulmonary tuberculosis (TB) treatment in an adult artisanal miner in eastern Democratic Republic of Congo. Xpert MTB/RIF was positive after his second rifampicin-susceptible TB treatment. Chest X-rays were suggestive of large cavity, fibrosis of remaining lung and air-fluid levels at the base of the destroyed lung. The patient passed away after delayed effective TB regimens. Clinicians should be aware that urgent surgical intervention is often required to prevent lethal acute respiratory failure and shock notwithstanding effective chemotherapy in such condition. Effort is needed to timely diagnose multidrug resistance TB and to implement thoracic surgery for TB in high burden countries. Elsevier 2020-09-28 /pmc/articles/PMC7582097/ /pubmed/33117645 http://dx.doi.org/10.1016/j.rmcr.2020.101234 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Katoto, Patrick D.M.C.
Musole, Patrick
Maheshe, Ghislain
Bamuleke, Bertrand
Murhula, Aime
Balungwe, Patrick
Byamungu, Liliane N.
A miner with No left lung: Extensive pulmonary destruction in delayed effective Multi-Drug-Resistant Tuberculosis treatment
title A miner with No left lung: Extensive pulmonary destruction in delayed effective Multi-Drug-Resistant Tuberculosis treatment
title_full A miner with No left lung: Extensive pulmonary destruction in delayed effective Multi-Drug-Resistant Tuberculosis treatment
title_fullStr A miner with No left lung: Extensive pulmonary destruction in delayed effective Multi-Drug-Resistant Tuberculosis treatment
title_full_unstemmed A miner with No left lung: Extensive pulmonary destruction in delayed effective Multi-Drug-Resistant Tuberculosis treatment
title_short A miner with No left lung: Extensive pulmonary destruction in delayed effective Multi-Drug-Resistant Tuberculosis treatment
title_sort miner with no left lung: extensive pulmonary destruction in delayed effective multi-drug-resistant tuberculosis treatment
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582097/
https://www.ncbi.nlm.nih.gov/pubmed/33117645
http://dx.doi.org/10.1016/j.rmcr.2020.101234
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