Association of Uncommon, Noncoding Variants in the APOE Region With Risk of Alzheimer Disease in Adults of European Ancestry

IMPORTANCE: The ε2 and ε4 alleles of the apolipoprotein E (APOE) gene are associated with Alzheimer disease (AD) risk. Although nearby genetic variants have also been shown to be associated with AD, including rs2075650 in the TOMM40 gene and rs4420638 near the APOC1 gene, it is unknown whether these...

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Detalles Bibliográficos
Autores principales: Blue, Elizabeth E., Cheng, Anqi, Chen, Sunny, Yu, Chang-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582128/
https://www.ncbi.nlm.nih.gov/pubmed/33090224
http://dx.doi.org/10.1001/jamanetworkopen.2020.17666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582128/
https://www.ncbi.nlm.nih.gov/pubmed/33090224
http://dx.doi.org/10.1001/jamanetworkopen.2020.17666

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