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Phylogenetic and biochemical analysis of calsequestrin structure and association of its variants with cardiac disorders

Calsequestrin is among the most abundant proteins in muscle sarcoplasmic reticulum and displays a high capacity but a low affinity for Ca(2+) binding. In mammals, calsequestrin is encoded by two genes, CASQ1 and CASQ2, which are expressed almost exclusively in skeletal and cardiac muscles, respectiv...

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Detalles Bibliográficos
Autores principales:	Wang, Qian, Paskevicius, Tautvydas, Filbert, Alexander, Qin, Wenying, Kim, Hyeong Jin, Chen, Xing-Zhen, Tang, Jingfeng, Dacks, Joel B., Agellon, Luis B., Michalak, Marek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582152/ https://www.ncbi.nlm.nih.gov/pubmed/33093545 http://dx.doi.org/10.1038/s41598-020-75097-3

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