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CELF2 regulates the species-specific alternative splicing of TREM2

Genetic variations of TREM2 have been implicated as a risk factor of Alzheimer’s disease (AD). Recent studies suggest that the loss of TREM2 function compromises microglial responses to the accumulation of amyloid beta. Previously, we found that exon 3 of TREM2 is an alternative exon whose skipping...

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Detalles Bibliográficos
Autores principales:	Yanaizu, Motoaki, Washizu, Chika, Nukina, Nobuyuki, Satoh, Jun-ichi, Kino, Yoshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582162/ https://www.ncbi.nlm.nih.gov/pubmed/33093587 http://dx.doi.org/10.1038/s41598-020-75057-x

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