Synthesis, Biological Evaluation and Stability Studies of Some Novel Aza-Acridine Aminoderivatives

Several new amino-substituted aza-acridine derivatives bearing a basic side chain have been designed and synthesized. The antiproliferative activity of the target compounds has been evaluated against three cancer cell lines—namely HCT-116 (colorectal), the uterine sarcoma MES-SA, and its doxorubicin...

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Detalles Bibliográficos
Autores principales: Karelou, Maria, Kourafalos, Vasileios, Tragomalou, Athanasia P., Marakos, Panagiotis, Pouli, Nicole, Tsitsilonis, Ourania E., Gikas, Evangelos, Kostakis, Ioannis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582268/
https://www.ncbi.nlm.nih.gov/pubmed/33049986
http://dx.doi.org/10.3390/molecules25194584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582268/
https://www.ncbi.nlm.nih.gov/pubmed/33049986
http://dx.doi.org/10.3390/molecules25194584

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