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Accurate and Efficient Intracranial Hemorrhage Detection and Subtype Classification in 3D CT Scans with Convolutional and Long Short-Term Memory Neural Networks

In this paper, we present our system for the RSNA Intracranial Hemorrhage Detection challenge, which is based on the RSNA 2019 Brain CT Hemorrhage dataset. The proposed system is based on a lightweight deep neural network architecture composed of a convolutional neural network (CNN) that takes as in...

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Autores principales: Burduja, Mihail, Ionescu, Radu Tudor, Verga, Nicolae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582288/
https://www.ncbi.nlm.nih.gov/pubmed/33019508
http://dx.doi.org/10.3390/s20195611
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author Burduja, Mihail
Ionescu, Radu Tudor
Verga, Nicolae
author_facet Burduja, Mihail
Ionescu, Radu Tudor
Verga, Nicolae
author_sort Burduja, Mihail
collection PubMed
description In this paper, we present our system for the RSNA Intracranial Hemorrhage Detection challenge, which is based on the RSNA 2019 Brain CT Hemorrhage dataset. The proposed system is based on a lightweight deep neural network architecture composed of a convolutional neural network (CNN) that takes as input individual CT slices, and a Long Short-Term Memory (LSTM) network that takes as input multiple feature embeddings provided by the CNN. For efficient processing, we consider various feature selection methods to produce a subset of useful CNN features for the LSTM. Furthermore, we reduce the CT slices by a factor of [Formula: see text] , which enables us to train the model faster. Even if our model is designed to balance speed and accuracy, we report a weighted mean log loss of [Formula: see text] on the final test set, which places us in the top 30 ranking (2%) from a total of 1345 participants. While our computing infrastructure does not allow it, processing CT slices at their original scale is likely to improve performance. In order to enable others to reproduce our results, we provide our code as open source. After the challenge, we conducted a subjective intracranial hemorrhage detection assessment by radiologists, indicating that the performance of our deep model is on par with that of doctors specialized in reading CT scans. Another contribution of our work is to integrate Grad-CAM visualizations in our system, providing useful explanations for its predictions. We therefore consider our system as a viable option when a fast diagnosis or a second opinion on intracranial hemorrhage detection are needed.
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spelling pubmed-75822882020-10-28 Accurate and Efficient Intracranial Hemorrhage Detection and Subtype Classification in 3D CT Scans with Convolutional and Long Short-Term Memory Neural Networks Burduja, Mihail Ionescu, Radu Tudor Verga, Nicolae Sensors (Basel) Article In this paper, we present our system for the RSNA Intracranial Hemorrhage Detection challenge, which is based on the RSNA 2019 Brain CT Hemorrhage dataset. The proposed system is based on a lightweight deep neural network architecture composed of a convolutional neural network (CNN) that takes as input individual CT slices, and a Long Short-Term Memory (LSTM) network that takes as input multiple feature embeddings provided by the CNN. For efficient processing, we consider various feature selection methods to produce a subset of useful CNN features for the LSTM. Furthermore, we reduce the CT slices by a factor of [Formula: see text] , which enables us to train the model faster. Even if our model is designed to balance speed and accuracy, we report a weighted mean log loss of [Formula: see text] on the final test set, which places us in the top 30 ranking (2%) from a total of 1345 participants. While our computing infrastructure does not allow it, processing CT slices at their original scale is likely to improve performance. In order to enable others to reproduce our results, we provide our code as open source. After the challenge, we conducted a subjective intracranial hemorrhage detection assessment by radiologists, indicating that the performance of our deep model is on par with that of doctors specialized in reading CT scans. Another contribution of our work is to integrate Grad-CAM visualizations in our system, providing useful explanations for its predictions. We therefore consider our system as a viable option when a fast diagnosis or a second opinion on intracranial hemorrhage detection are needed. MDPI 2020-10-01 /pmc/articles/PMC7582288/ /pubmed/33019508 http://dx.doi.org/10.3390/s20195611 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Burduja, Mihail
Ionescu, Radu Tudor
Verga, Nicolae
Accurate and Efficient Intracranial Hemorrhage Detection and Subtype Classification in 3D CT Scans with Convolutional and Long Short-Term Memory Neural Networks
title Accurate and Efficient Intracranial Hemorrhage Detection and Subtype Classification in 3D CT Scans with Convolutional and Long Short-Term Memory Neural Networks
title_full Accurate and Efficient Intracranial Hemorrhage Detection and Subtype Classification in 3D CT Scans with Convolutional and Long Short-Term Memory Neural Networks
title_fullStr Accurate and Efficient Intracranial Hemorrhage Detection and Subtype Classification in 3D CT Scans with Convolutional and Long Short-Term Memory Neural Networks
title_full_unstemmed Accurate and Efficient Intracranial Hemorrhage Detection and Subtype Classification in 3D CT Scans with Convolutional and Long Short-Term Memory Neural Networks
title_short Accurate and Efficient Intracranial Hemorrhage Detection and Subtype Classification in 3D CT Scans with Convolutional and Long Short-Term Memory Neural Networks
title_sort accurate and efficient intracranial hemorrhage detection and subtype classification in 3d ct scans with convolutional and long short-term memory neural networks
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582288/
https://www.ncbi.nlm.nih.gov/pubmed/33019508
http://dx.doi.org/10.3390/s20195611
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