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Is the Secret of VDAC Isoforms in Their Gene Regulation? Characterization of Human VDAC Genes Expression Profile, Promoter Activity, and Transcriptional Regulators
VDACs (voltage-dependent anion-selective channels) are pore-forming proteins of the outer mitochondrial membrane, whose permeability is primarily due to VDACs’ presence. In higher eukaryotes, three isoforms are raised during the evolution: they have the same exon–intron organization, and the protein...
Autores principales: | Zinghirino, Federica, Pappalardo, Xena Giada, Messina, Angela, Guarino, Francesca, De Pinto, Vito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582299/ https://www.ncbi.nlm.nih.gov/pubmed/33036380 http://dx.doi.org/10.3390/ijms21197388 |
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