Cargando…
Regenerative Response of Degenerate Human Nucleus Pulposus Cells to GDF6 Stimulation
Growth differentiation factor (GDF) family members have been implicated in the development and maintenance of healthy nucleus pulposus (NP) tissue, making them promising therapeutic candidates for treatment of intervertebral disc (IVD) degeneration and associated back pain. GDF6 has been shown to pr...
Autores principales: | Hodgkinson, Tom, Gilbert, Hamish T. J., Pandya, Tej, Diwan, Ashish D., Hoyland, Judith A., Richardson, Stephen M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582366/ https://www.ncbi.nlm.nih.gov/pubmed/32992671 http://dx.doi.org/10.3390/ijms21197143 |
Ejemplares similares
-
Degenerate intervertebral disc‐like pH induces a catabolic mechanoresponse in human nucleus pulposus cells
por: Hodson, Nathan W., et al.
Publicado: (2018) -
Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration
por: Richardson, Stephen M., et al.
Publicado: (2017) -
Degenerate Human Nucleus Pulposus Cells Promote Neurite Outgrowth in Neural Cells
por: Richardson, Stephen M., et al.
Publicado: (2012) -
Microparticles for controlled growth differentiation factor 6 delivery to direct adipose stem cell‐based nucleus pulposus regeneration
por: Hodgkinson, Tom, et al.
Publicado: (2019) -
High BMPR2 expression leads to enhanced SMAD1/5/8 signalling and GDF6
responsiveness in human adipose-derived stem cells: implications for stem cell
therapies for intervertebral disc degeneration
por: Hodgkinson, Tom, et al.
Publicado: (2020)