Histone-Mutant Glioma: Molecular Mechanisms, Preclinical Models, and Implications for Therapy

Pediatric high-grade glioma (pHGG) is the leading cause of cancer death in children. Despite histologic similarities, it has recently become apparent that this disease is molecularly distinct from its adult counterpart. Specific hallmark oncogenic histone mutations within pediatric malignant gliomas...

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Detalles Bibliográficos
Autores principales: Graham, Maya S., Mellinghoff, Ingo K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582376/
https://www.ncbi.nlm.nih.gov/pubmed/33003625
http://dx.doi.org/10.3390/ijms21197193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582376/
https://www.ncbi.nlm.nih.gov/pubmed/33003625
http://dx.doi.org/10.3390/ijms21197193

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