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Histone-Mutant Glioma: Molecular Mechanisms, Preclinical Models, and Implications for Therapy
Pediatric high-grade glioma (pHGG) is the leading cause of cancer death in children. Despite histologic similarities, it has recently become apparent that this disease is molecularly distinct from its adult counterpart. Specific hallmark oncogenic histone mutations within pediatric malignant gliomas...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582376/ https://www.ncbi.nlm.nih.gov/pubmed/33003625 http://dx.doi.org/10.3390/ijms21197193 |