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Ring-Closing Metathesis Approaches towards the Total Synthesis of Rhizoxins

Efforts are described towards the total synthesis of the bacterial macrolide rhizoxin F, which is a potent tubulin assembly and cancer cell growth inhibitor. A significant amount of work was expanded on the construction of the rhizoxin core macrocycle by ring-closing olefin metathesis (RCM) between...

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Detalles Bibliográficos
Autores principales:	Liniger, Marc, Neuhaus, Christian M., Altmann, Karl-Heinz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582377/ https://www.ncbi.nlm.nih.gov/pubmed/33023218 http://dx.doi.org/10.3390/molecules25194527

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