Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity

Two mononuclear Pd(II) complexes [PdCl(2)(pfptp)] (1) and [PdCl(2)(pfhtp)] (2), with ligands 2-(3-perfluoropropyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfptp) and 2-(3-perfluoroheptyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfhtp), were synthesized and structurally characterized. The two complexes s...

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Detalles Bibliográficos
Autores principales: Rubino, Simona, Alduina, Rosa, Cancemi, Patrizia, Girasolo, Maria Assunta, Di Stefano, Vita, Orecchio, Santino, Buscemi, Silvestre, Pibiri, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582383/
https://www.ncbi.nlm.nih.gov/pubmed/33007913
http://dx.doi.org/10.3390/molecules25194487
Descripción
Sumario:Two mononuclear Pd(II) complexes [PdCl(2)(pfptp)] (1) and [PdCl(2)(pfhtp)] (2), with ligands 2-(3-perfluoropropyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfptp) and 2-(3-perfluoroheptyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfhtp), were synthesized and structurally characterized. The two complexes showed a bidentate coordination of the ligand occurring through N atom of pyridine ring and N4 atom of 1,2,4-triazole. Both complexes showed antimicrobial activity when tested against both Gram-negative and Gram-positive bacterial strains.

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