Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity

Two mononuclear Pd(II) complexes [PdCl(2)(pfptp)] (1) and [PdCl(2)(pfhtp)] (2), with ligands 2-(3-perfluoropropyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfptp) and 2-(3-perfluoroheptyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfhtp), were synthesized and structurally characterized. The two complexes s...

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Autores principales: Rubino, Simona, Alduina, Rosa, Cancemi, Patrizia, Girasolo, Maria Assunta, Di Stefano, Vita, Orecchio, Santino, Buscemi, Silvestre, Pibiri, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582383/
https://www.ncbi.nlm.nih.gov/pubmed/33007913
http://dx.doi.org/10.3390/molecules25194487
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author Rubino, Simona
Alduina, Rosa
Cancemi, Patrizia
Girasolo, Maria Assunta
Di Stefano, Vita
Orecchio, Santino
Buscemi, Silvestre
Pibiri, Ivana
author_facet Rubino, Simona
Alduina, Rosa
Cancemi, Patrizia
Girasolo, Maria Assunta
Di Stefano, Vita
Orecchio, Santino
Buscemi, Silvestre
Pibiri, Ivana
author_sort Rubino, Simona
collection PubMed
description Two mononuclear Pd(II) complexes [PdCl(2)(pfptp)] (1) and [PdCl(2)(pfhtp)] (2), with ligands 2-(3-perfluoropropyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfptp) and 2-(3-perfluoroheptyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfhtp), were synthesized and structurally characterized. The two complexes showed a bidentate coordination of the ligand occurring through N atom of pyridine ring and N4 atom of 1,2,4-triazole. Both complexes showed antimicrobial activity when tested against both Gram-negative and Gram-positive bacterial strains.
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spelling pubmed-75823832020-10-29 Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity Rubino, Simona Alduina, Rosa Cancemi, Patrizia Girasolo, Maria Assunta Di Stefano, Vita Orecchio, Santino Buscemi, Silvestre Pibiri, Ivana Molecules Communication Two mononuclear Pd(II) complexes [PdCl(2)(pfptp)] (1) and [PdCl(2)(pfhtp)] (2), with ligands 2-(3-perfluoropropyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfptp) and 2-(3-perfluoroheptyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfhtp), were synthesized and structurally characterized. The two complexes showed a bidentate coordination of the ligand occurring through N atom of pyridine ring and N4 atom of 1,2,4-triazole. Both complexes showed antimicrobial activity when tested against both Gram-negative and Gram-positive bacterial strains. MDPI 2020-09-30 /pmc/articles/PMC7582383/ /pubmed/33007913 http://dx.doi.org/10.3390/molecules25194487 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Rubino, Simona
Alduina, Rosa
Cancemi, Patrizia
Girasolo, Maria Assunta
Di Stefano, Vita
Orecchio, Santino
Buscemi, Silvestre
Pibiri, Ivana
Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity
title Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity
title_full Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity
title_fullStr Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity
title_full_unstemmed Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity
title_short Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity
title_sort mononuclear perfluoroalkyl-heterocyclic complexes of pd(ii): synthesis, structural characterization and antimicrobial activity
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582383/
https://www.ncbi.nlm.nih.gov/pubmed/33007913
http://dx.doi.org/10.3390/molecules25194487
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