Cargando…
Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series
OBJECTIVE: We aimed to describe the features of 220 nonemergency (mild or common type) COVID-19 patients from a shelter hospital, as well as evaluate the efficiency of antiviral drug, Arbidol in their disease progressions. METHODS: Basic clinical characteristics were described and the efficacy of Ar...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582420/ https://www.ncbi.nlm.nih.gov/pubmed/33097047 http://dx.doi.org/10.1186/s12985-020-01428-5 |
_version_ | 1783599187415269376 |
---|---|
author | Gao, Wei Chen, Si Wang, Kun Chen, Rongzhang Guo, Qian Lu, Jingjing Wu, Xiaodong He, Yanan Yan, Qiaoyun Wang, Shengyun Wang, Feilong Jin, Li Hua, Jing Li, Qiang |
author_facet | Gao, Wei Chen, Si Wang, Kun Chen, Rongzhang Guo, Qian Lu, Jingjing Wu, Xiaodong He, Yanan Yan, Qiaoyun Wang, Shengyun Wang, Feilong Jin, Li Hua, Jing Li, Qiang |
author_sort | Gao, Wei |
collection | PubMed |
description | OBJECTIVE: We aimed to describe the features of 220 nonemergency (mild or common type) COVID-19 patients from a shelter hospital, as well as evaluate the efficiency of antiviral drug, Arbidol in their disease progressions. METHODS: Basic clinical characteristics were described and the efficacy of Arbidol was evaluated based on gender, age, maximum body temperature of the patients. RESULTS: Basically, males had a higher risk of fever and more onset symptoms than females. Arbidol could accelerate fever recovery and viral clearance in respiratory specimens, particularly in males. Arbidol also contributed to shorter hospital stay without obvious adverse reactions. CONCLUSIONS: In the retrospective COVID-19 cohort, gender was one of the important factors affecting patient's conditions. Arbidol showed several beneficial effects in these patients, especially in males. This study brought more researches enlightenment in understanding the emerging infectious disease. |
format | Online Article Text |
id | pubmed-7582420 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-75824202020-10-23 Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series Gao, Wei Chen, Si Wang, Kun Chen, Rongzhang Guo, Qian Lu, Jingjing Wu, Xiaodong He, Yanan Yan, Qiaoyun Wang, Shengyun Wang, Feilong Jin, Li Hua, Jing Li, Qiang Virol J Short Report OBJECTIVE: We aimed to describe the features of 220 nonemergency (mild or common type) COVID-19 patients from a shelter hospital, as well as evaluate the efficiency of antiviral drug, Arbidol in their disease progressions. METHODS: Basic clinical characteristics were described and the efficacy of Arbidol was evaluated based on gender, age, maximum body temperature of the patients. RESULTS: Basically, males had a higher risk of fever and more onset symptoms than females. Arbidol could accelerate fever recovery and viral clearance in respiratory specimens, particularly in males. Arbidol also contributed to shorter hospital stay without obvious adverse reactions. CONCLUSIONS: In the retrospective COVID-19 cohort, gender was one of the important factors affecting patient's conditions. Arbidol showed several beneficial effects in these patients, especially in males. This study brought more researches enlightenment in understanding the emerging infectious disease. BioMed Central 2020-10-23 /pmc/articles/PMC7582420/ /pubmed/33097047 http://dx.doi.org/10.1186/s12985-020-01428-5 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Short Report Gao, Wei Chen, Si Wang, Kun Chen, Rongzhang Guo, Qian Lu, Jingjing Wu, Xiaodong He, Yanan Yan, Qiaoyun Wang, Shengyun Wang, Feilong Jin, Li Hua, Jing Li, Qiang Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series |
title | Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series |
title_full | Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series |
title_fullStr | Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series |
title_full_unstemmed | Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series |
title_short | Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series |
title_sort | clinical features and efficacy of antiviral drug, arbidol in 220 nonemergency covid‐19 patients from east-west-lake shelter hospital in wuhan: a retrospective case series |
topic | Short Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582420/ https://www.ncbi.nlm.nih.gov/pubmed/33097047 http://dx.doi.org/10.1186/s12985-020-01428-5 |
work_keys_str_mv | AT gaowei clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT chensi clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT wangkun clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT chenrongzhang clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT guoqian clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT lujingjing clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT wuxiaodong clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT heyanan clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT yanqiaoyun clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT wangshengyun clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT wangfeilong clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT jinli clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT huajing clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries AT liqiang clinicalfeaturesandefficacyofantiviraldrugarbidolin220nonemergencycovid19patientsfromeastwestlakeshelterhospitalinwuhanaretrospectivecaseseries |